Author's response to reviews Title:Tumor Cells With Low Proteasome Subunit Expression Predict Overall Survival in Head and Neck Cancer Patients Authors:

Determining the Prognostic Factors of Survival in Patients with Head and Neck Cancer Using Parametric Models and Cox Bayesian Model, from 2007 to 2013

Introduction: Head and neck cancer is one of the most important cancers with low survival. This study was designed to evaluate the one-year survival of patients with head and neck cancer and related demographic factors. Methods: The present study was a cross-sectional study that reviewed the records of the patients with head and neck cancer (193 patients) in 2007-2013. In this study, Kaplan-Me...

Author's response to reviews Title: Pretreatment organ function in patients with advanced head and neck cancer: Clinical outcome measures and Patients' views Authors:

Synergistic Anti-Cancer Effects of Second-Generation Proteasome Inhibitor Carfilzomib with Doxorubicin and Dexamethasone Via p53-Mediated Apoptosis in Pre-B Acute Lymphoblastic Leukemia Cells

Background: The ubiquitin-proteasome system (UPS) plays a crucial role in regulating the levels and functions of a large number of proteins in the cell, which are important for cancer cell growth and survival. The proteasome is highly activated in B-cell precursor acute lymphoblastic leukemia (BCP-ALL), which is the most common malignancy in children. The attempt to inhibit proteasome as a ther...

Author's response to reviews Title: A cost-effectiveness analysis of a preventive exercise program for patients with advanced head and neck cancer treated with concomitant chemo-radiotherapy Authors:

Investigation of HER-2 expression and its Correlation with clinicopathological parameters and overall survival of esophageal squamous cell carcinoma patients

Background & Objective: Human epidermal growth factor receptor 2 (HER-2) exhibits a vast range of expression in esophageal squamous...